Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice

The present study aimed to investigate cognitive dysfunction in the hippocampus induced by sepsis-associated encephalopathy (SAE) via acetylation of cyclophilin D (CypD) and opening of mitochondrial permeability transition pore. It also explored whether activating sirtuin 3 (SIRT3) can mediate deace...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Mol Neurobiol
Main Authors: Sun, Fan, Si, Yanna, Bao, Hongguang, Xu, Yajie, Pan, XiaoXiao, Zeng, Lingqing, Jing, Ling
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2017
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630658/
https://ncbi.nlm.nih.gov/pubmed/28236057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-017-0476-2
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