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Effects of α-conotoxin ImI on TNF-α, IL-8 and TGF-β expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells

α7 nicotinic acetylcholine receptors (nAChRs) are ubiquitous in the nervous system and ensure important neurophysiological functionality for many processes. However, they are also found in cells of the immune system, where their role has been less studied. Here we report the pro-inflammatory effect...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Padilla, Alberto, Keating, Patricia, Hartmann, James X., Marí, Frank
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630575/
https://ncbi.nlm.nih.gov/pubmed/28986583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11586-2
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