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Effects of α-conotoxin ImI on TNF-α, IL-8 and TGF-β expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells

α7 nicotinic acetylcholine receptors (nAChRs) are ubiquitous in the nervous system and ensure important neurophysiological functionality for many processes. However, they are also found in cells of the immune system, where their role has been less studied. Here we report the pro-inflammatory effect...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Padilla, Alberto, Keating, Patricia, Hartmann, James X., Marí, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630575/
https://ncbi.nlm.nih.gov/pubmed/28986583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11586-2
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