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Effects of α-conotoxin ImI on TNF-α, IL-8 and TGF-β expression by human macrophage-like cells derived from THP-1 pre-monocytic leukemic cells

α7 nicotinic acetylcholine receptors (nAChRs) are ubiquitous in the nervous system and ensure important neurophysiological functionality for many processes. However, they are also found in cells of the immune system, where their role has been less studied. Here we report the pro-inflammatory effect...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Padilla, Alberto, Keating, Patricia, Hartmann, James X., Marí, Frank
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630575/
https://ncbi.nlm.nih.gov/pubmed/28986583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11586-2
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