Generation and characterization of ErbB2-CAR-engineered cytokine-induced killer cells for the treatment of high-risk soft tissue sarcoma in children

Pediatric patients with recurrent, refractory or advanced soft tissue sarcoma (STS) who are simultaneously showing signs of cumulative treatment toxicity are in need of novel therapies. In this preclinical analysis, we identified ErbB2 as a targetable antigen on STS cells and used cytokine-induced k...

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Vydáno v:Oncotarget
Hlavní autoři: Merker, Michael, Pfirrmann, Verena, Oelsner, Sarah, Fulda, Simone, Klingebiel, Thomas, Wels, Winfried S., Bader, Peter, Rettinger, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630399/
https://ncbi.nlm.nih.gov/pubmed/29029499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19821
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