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Generation and characterization of ErbB2-CAR-engineered cytokine-induced killer cells for the treatment of high-risk soft tissue sarcoma in children

Pediatric patients with recurrent, refractory or advanced soft tissue sarcoma (STS) who are simultaneously showing signs of cumulative treatment toxicity are in need of novel therapies. In this preclinical analysis, we identified ErbB2 as a targetable antigen on STS cells and used cytokine-induced k...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Merker, Michael, Pfirrmann, Verena, Oelsner, Sarah, Fulda, Simone, Klingebiel, Thomas, Wels, Winfried S., Bader, Peter, Rettinger, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630399/
https://ncbi.nlm.nih.gov/pubmed/29029499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19821
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