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A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer

RESULTS: SPC24 is over-expressed in clinical lung adenocarcinoma samples, and high level of SPC24 is associated with advanced stages of lung tumors. Knocking down SPC24 repressed cell growth and promoted apoptosis. SPC24 deficiency reduced cancer cell migration as well. E-cadherin, one of the epithe...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Zhou, Juan, Yu, Yang, Pei, Yunfeng, Cao, Chunping, Ding, Chen, Wang, Duping, Sun, Li, Niu, Guoping
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630346/
https://ncbi.nlm.nih.gov/pubmed/29029446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18971
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