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A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer

RESULTS: SPC24 is over-expressed in clinical lung adenocarcinoma samples, and high level of SPC24 is associated with advanced stages of lung tumors. Knocking down SPC24 repressed cell growth and promoted apoptosis. SPC24 deficiency reduced cancer cell migration as well. E-cadherin, one of the epithe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhou, Juan, Yu, Yang, Pei, Yunfeng, Cao, Chunping, Ding, Chen, Wang, Duping, Sun, Li, Niu, Guoping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630346/
https://ncbi.nlm.nih.gov/pubmed/29029446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18971
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