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A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer

RESULTS: SPC24 is over-expressed in clinical lung adenocarcinoma samples, and high level of SPC24 is associated with advanced stages of lung tumors. Knocking down SPC24 repressed cell growth and promoted apoptosis. SPC24 deficiency reduced cancer cell migration as well. E-cadherin, one of the epithe...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Juan, Yu, Yang, Pei, Yunfeng, Cao, Chunping, Ding, Chen, Wang, Duping, Sun, Li, Niu, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630346/
https://ncbi.nlm.nih.gov/pubmed/29029446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18971
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