Abnormalities in perineuronal nets and behavior in mice lacking CSGalNAcT1, a key enzyme in chondroitin sulfate synthesis

Chondroitin sulfate (CS) is an important glycosaminoglycan and is mainly found in the extracellular matrix as CS proteoglycans. In the brain, CS proteoglycans are highly concentrated in perineuronal nets (PNNs), which surround synapses and modulate their functions. To investigate the importance of C...

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Bibliographic Details
Published in:Mol Brain
Main Authors: Yoshioka, Nozomu, Miyata, Shinji, Tamada, Atsushi, Watanabe, Yumi, Kawasaki, Asami, Kitagawa, Hiroshi, Takao, Keizo, Miyakawa, Tsuyoshi, Takeuchi, Kosei, Igarashi, Michihiro
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629790/
https://ncbi.nlm.nih.gov/pubmed/28982363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0328-5
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