Chondroitin Sulfate Is Required for Onset and Offset of Critical Period Plasticity in Visual Cortex

Ocular dominance plasticity is easily observed during the critical period in early postnatal life. Chondroitin sulfate (CS) is the most abundant component in extracellular structures called perineuronal nets (PNNs), which surround parvalbumin-expressing interneurons (PV-cells). CS accumulates in PNN...

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Publicado no:Sci Rep
Main Authors: Hou, Xubin, Yoshioka, Nozomu, Tsukano, Hiroaki, Sakai, Akiko, Miyata, Shinji, Watanabe, Yumi, Yanagawa, Yuchio, Sakimura, Kenji, Takeuchi, Kosei, Kitagawa, Hiroshi, Hensch, Takao K., Shibuki, Katsuei, Igarashi, Michihiro, Sugiyama, Sayaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626782/
https://ncbi.nlm.nih.gov/pubmed/28974755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04007-x
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