Cystic fibrosis swine fail to secrete airway surface liquid in response to inhalation of pathogens

Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) channel, which can result in chronic lung disease. The sequence of events leading to lung disease is not fully understood but recent data show that the critical pathogenic event...

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Pubblicato in:Nat Commun
Autori principali: Luan, Xiaojie, Belev, George, Tam, Julian S., Jagadeeshan, Santosh, Hassan, Noman, Gioino, Paula, Grishchenko, Nikolay, Huang, Yanyun, Carmalt, James L., Duke, Tanya, Jones, Teela, Monson, Bev, Burmester, Monique, Simovich, Tomer, Yilmaz, Orhan, Campanucci, Veronica A., Machen, Terry E., Chapman, L. Dean, Ianowski, Juan P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629252/
https://ncbi.nlm.nih.gov/pubmed/28983075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00835-7
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