Cystic fibrosis swine fail to secrete airway surface liquid in response to inhalation of pathogens

Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) channel, which can result in chronic lung disease. The sequence of events leading to lung disease is not fully understood but recent data show that the critical pathogenic event...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Luan, Xiaojie, Belev, George, Tam, Julian S., Jagadeeshan, Santosh, Hassan, Noman, Gioino, Paula, Grishchenko, Nikolay, Huang, Yanyun, Carmalt, James L., Duke, Tanya, Jones, Teela, Monson, Bev, Burmester, Monique, Simovich, Tomer, Yilmaz, Orhan, Campanucci, Veronica A., Machen, Terry E., Chapman, L. Dean, Ianowski, Juan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629252/
https://ncbi.nlm.nih.gov/pubmed/28983075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00835-7
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