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Cancer immunotherapy—immune checkpoint blockade and associated endocrinopathies

Advances in cancer therapy in the past few years have include the development of medications that modulate immune checkpoint proteins. Cytotoxic T-lymphocyte antigen 4 (CTLA4) and programmed death 1 (PD1), are two coinhibitory receptors that are expressed on activated T cells to which therapeutic bl...

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Bibliographic Details
Published in:Nat Rev Endocrinol
Main Authors: Byun, David J., Wolchok, Jedd D., Rosenberg, Lynne M., Girotra, Monica
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629093/
https://ncbi.nlm.nih.gov/pubmed/28106152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrendo.2016.205
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