Insulin Receptor Isoforms in Physiology and Disease: An Updated View

The insulin receptor (IR) gene undergoes differential splicing that generates two IR isoforms, IR-A and IR-B. The physiological roles of IR isoforms are incompletely understood and appear to be determined by their different binding affinities for insulin-like growth factors (IGFs), particularly for...

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書目詳細資料
發表在:Endocr Rev
Main Authors: Belfiore, Antonino, Malaguarnera, Roberta, Vella, Veronica, Lawrence, Michael C., Sciacca, Laura, Frasca, Francesco, Morrione, Andrea, Vigneri, Riccardo
格式: Artigo
語言:Inglês
出版: Endocrine Society 2017
主題:
Reviews
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629070/
https://ncbi.nlm.nih.gov/pubmed/28973479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2017-00073
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