Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of Mikania variifolia and Mikania micrantha dichloromethane extracts. Mikanolide and deoxymikanolide were the major compounds in both extracts (2.2% and 0.4%...

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Udgivet i:PLoS Negl Trop Dis
Main Authors: Laurella, Laura C., Cerny, Natacha, Bivona, Augusto E., Sánchez Alberti, Andrés, Giberti, Gustavo, Malchiodi, Emilio L., Martino, Virginia S., Catalan, Cesar A., Alonso, María Rosario, Cazorla, Silvia I., Sülsen, Valeria P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629014/
https://ncbi.nlm.nih.gov/pubmed/28945741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005929
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