Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Four sesquiterpene lactones, mikanolide, deoxymikanolide, dihydromikanolide and scandenolide, were isolated by a bioassay-guided fractionation of Mikania variifolia and Mikania micrantha dichloromethane extracts. Mikanolide and deoxymikanolide were the major compounds in both extracts (2.2% and 0.4%...

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Опубликовано в: :PLoS Negl Trop Dis
Главные авторы: Laurella, Laura C., Cerny, Natacha, Bivona, Augusto E., Sánchez Alberti, Andrés, Giberti, Gustavo, Malchiodi, Emilio L., Martino, Virginia S., Catalan, Cesar A., Alonso, María Rosario, Cazorla, Silvia I., Sülsen, Valeria P.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629014/
https://ncbi.nlm.nih.gov/pubmed/28945741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005929
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