Encapsulation of ropivacaine in a combined (donor-acceptor, ionic-gradient) liposomal system promotes extended anesthesia time

Ropivacaine is a local anesthetic with similar potency but lower systemic toxicity than bupivacaine, the most commonly used spinal anesthetic. The present study concerns the development of a combined drug delivery system for ropivacaine, comprised of two types of liposomes: donor multivesicular vesi...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: da Silva, Camila Morais Gonçalves, Franz-Montan, Michelle, Limia, Cíntia Elisabeth Gomez, Ribeiro, Lígia Nunes de Morais, Braga, Mário Antônio, Guilherme, Viviane Aparecida, da Silva, Camila Batista, Casadei, Bruna Renata, Cereda, Cíntia Maria Saia, de Paula, Eneida
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628885/
https://ncbi.nlm.nih.gov/pubmed/28982145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185828
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