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NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X

NIMA-related kinase 1 (NEK1) is a serine/threonine and tyrosine kinase that is highly expressed in mammalian germ cells. Mutations in Nek1 induce anemia, polycystic kidney and infertility. In this study we evaluated the role of NEK1 in meiotic spindle formation in both male and female gametes. Our r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brieño-Enríquez, Miguel A., Moak, Stefannie L., Holloway, J. Kim, Cohen, Paula E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628868/
https://ncbi.nlm.nih.gov/pubmed/28982183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185780
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