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The folded k-spectrum kernel: A machine learning approach to detecting transcription factor binding sites with gapped nucleotide dependencies

Understanding the molecular machinery involved in transcriptional regulation is central to improving our knowledge of an organism’s development, disease, and evolution. The building blocks of this complex molecular machinery are an organism’s genomic DNA sequence and transcription factor proteins. D...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Elmas, Abdulkadir, Wang, Xiaodong, Dresch, Jacqueline M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628859/
https://ncbi.nlm.nih.gov/pubmed/28982128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185570
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