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Discriminating between HuR and TTP binding sites using the k-spectrum kernel method

BACKGROUND: The RNA binding proteins (RBPs) human antigen R (HuR) and Tristetraprolin (TTP) are known to exhibit competitive binding but have opposing effects on the bound messenger RNA (mRNA). How cells discriminate between the two proteins is an interesting problem. Machine learning approaches, su...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Bhandare, Shweta, Goldberg, Debra S., Dowell, Robin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363848/
https://ncbi.nlm.nih.gov/pubmed/28333956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174052
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