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Mutation analysis of the CTNS gene in Iranian patients with infantile nephropathic cystinosis: identification of two novel mutations

Nephropathic cystinosis is an inherited lysosomal transport disorder caused by mutations in the CTNS gene that encodes for a lysosomal membrane transporter, cystinosin. Dysfunction in this protein leads to cystine accumulation in the cells of different organs. The accumulation of cystine in the kidn...

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書目詳細資料
發表在:Hum Genome Var
Main Authors: Sadeghipour, Forough, Basiratnia, Mitra, Derakhshan, Ali, Fardaei, Majid
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628181/
https://ncbi.nlm.nih.gov/pubmed/28983406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hgv.2017.38
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