Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

Cholangiocarcinoma (CCA) is a hepatobiliary malignancy exhibiting high incidence in countries with endemic liver-fluke infection. We analysed 489 CCAs from 10 countries, combining whole-genome (71 cases), targeted/exome, copy-number, gene expression, and DNA methylation information. Integrative clus...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Jusakul, Apinya, Cutcutache, Ioana, Yong, Chern Han, Lim, Jing Quan, Huang, Mi Ni, Padmanabhan, Nisha, Nellore, Vishwa, Kongpetch, Sarinya, Ng, Alvin Wei Tian, Ng, Ley Moy, Choo, Su Pin, Myint, Swe Swe, Thanan, Raynoo, Nagarajan, Sanjanaa, Lim, Weng Khong, Ng, Cedric Chuan Young, Boot, Arnoud, Liu, Mo, Ong, Choon Kiat, Rajasegaran, Vikneswari, Lie, Stefanus, Lim, Alvin Soon Tiong, Lim, Tse Hui, Tan, Jing, Loh, Jia Liang, McPherson, John R., Khuntikeo, Narong, Bhudhisawasdi, Vajaraphongsa, Yongvanit, Puangrat, Wongkham, Sopit, Totoki, Yasushi, Nakamura, Hiromi, Arai, Yasuhito, Yamasaki, Satoshi, Chow, Pierce Kah-Hoe, Chung, Alexander Yaw Fui, Ooi, London Lucien Peng Jin, Lim, Kiat Hon, Dima, Simona, Duda, Dan G., Popescu, Irinel, Broet, Philippe, Hsieh, Sen-Yung, Yu, Ming-Chin, Scarpa, Aldo, Lai, Jiaming, Luo, Di-Xian, Carvalho, André Lopes, Vettore, André Luiz, Rhee, Hyungjin, Park, Young Nyun, Alexandrov, Ludmil B., Gordân, Raluca, Rozen, Steven G., Shibata, Tatsuhiro, Pairojkul, Chawalit, Teh, Bin Tean, Tan, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628134/
https://ncbi.nlm.nih.gov/pubmed/28667006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0368
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