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Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103+ dendritic cell populations following respiratory infection

The CD103+ subset of lung migratory dendritic cells (DCs) plays an important role in the generation of CD8+ T cell responses following respiratory infection. Here, we demonstrate that the dependence on CD103+ DCs for stimulation of RSV-specific T cells is both epitope and age-dependent. CD103+ DCs i...

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Publicat a:Mucosal Immunol
Autors principals: Ruckwardt, Tracy J, Morabito, Kaitlyn M, Bar-Haim, Erez, Nair, Deepika, Graham, Barney S
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628111/
https://ncbi.nlm.nih.gov/pubmed/28378805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2017.28
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