Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase

Androgen deprivation therapy (ADT, surgical or chemical castration) is the mainstay treatment for metastatic prostate cancer (PCa); however, patients ineluctably relapse despite extremely low androgen levels. This evolution of PCa indicates its lethal progression. In this study, to mimic the traits...

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Bibliographic Details
Published in:Int J Mol Med
Main Authors: Yu, Pan, Duan, Xiuzhi, Cheng, Yue, Liu, Chunhua, Chen, Yuhua, Liu, Weiwei, Yin, Binbin, Wang, Xuchu, Tao, Zhihua
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627872/
https://ncbi.nlm.nih.gov/pubmed/28901378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3125
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