ELISA reagent coverage evaluation by affinity purification tandem mass spectrometry

Host cell proteins (HCPs) must be adequately removed from recombinant therapeutics by downstream processing to ensure patient safety, product quality, and regulatory compliance. HCP process clearance is typically monitored by enzyme-linked immunosorbent assay (ELISA) using a polyclonal reagent. Rece...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Henry, Scott M., Sutlief, Elissa, Salas-Solano, Oscar, Valliere-Douglass, John
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627587/
https://ncbi.nlm.nih.gov/pubmed/28708446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1349586
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