Building-block architecture of botulinum toxin complex: Conformational changes provide insights into the hemagglutination ability of the complex

Clostridium botulinum produces the botulinum neurotoxin (BoNT). Previously, we provided evidence for the “building-block” model of botulinum toxin complex (TC). In this model, a single BoNT is associated with a single nontoxic nonhemagglutinin (NTNHA), yielding M-TC; three HA-70 molecules are attach...

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Publicat a:Biochem Biophys Rep
Autors principals: Suzuki, Tomonori, Sagane, Yoshimasa, Matsumoto, Takashi, Hasegawa, Kimiko, Yamano, Akihito, Niwa, Koichi, Watanabe, Toshihiro
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627506/
https://ncbi.nlm.nih.gov/pubmed/29114581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.11.008
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