Botulinum Toxin Complex Increases Paracellular Permeability in Intestinal Epithelial Cells via Activation of p38 Mitogen-Activated Protein Kinase

Clostridium botulinum produces a large toxin complex (L-TC) that increases paracellular permeability in intestinal epithelial cells by a mechanism that remains unclear. Here, we show that mitogen-activated protein kinases (MAPKs) are involved in this permeability increase. Paracellular permeability...

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Главные авторы: MIYASHITA, Shin-ichiro, SAGANE, Yoshimasa, INUI, Ken, HAYASHI, Shintaro, MIYATA, Keita, SUZUKI, Tomonori, OHYAMA, Tohru, WATANABE, Toshihiro, NIWA, Koichi
Формат: Artigo
Язык:Inglês
Опубликовано: The Japanese Society of Veterinary Science 2013
Предметы:
Bacteriology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942962/
https://ncbi.nlm.nih.gov/pubmed/23884081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.13-0164
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