Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent from Interferons

BACKGROUND & AIMS: Tumor necrosis factor (TNF) an inflammatory cytokine expressed by human fetal liver cells (HFLCs) following infection with cell culture-derived hepatitis C virus. TNF has been reported to increase entry of HCV pseudoparticles into hepatoma cells and inhibit signaling by interf...

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Publicado en:Gastroenterology
Main Authors: Laidlaw, Stephen M., Marukian, Svetlana, Gilmore, Rachel H., Cashman, Siobhán B., Nechyporuk-Zloy, Volodymyr, Rice, Charles M., Dustin, Lynn B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627365/
https://ncbi.nlm.nih.gov/pubmed/28456632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.04.021
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