Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures

Hepatitis C virus (HCV) replication in primary liver cells is less robust than that in hepatoma cell lines, suggesting that innate antiviral mechanisms in primary cells may limit HCV replication or spread. Here, we analyzed expression of 47 genes associated with interferon (IFN) induction and signal...

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Huvudupphovsmän: Marukian, Svetlana, Andrus, Linda, Sheahan, Timothy P., Jones, Christopher T., Charles, Edgar D., Ploss, Alexander, Rice, Charles M., Dustin, Lynn B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219820/
https://ncbi.nlm.nih.gov/pubmed/21800339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24580
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