Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement

Genome dynamics are intimately linked to the regulation of gene expression, the most fundamental mechanism in biology, yet we still do not know whether the very process of transcription drives spatial organization at specific gene loci. Here, we have optimized the ANCHOR/ParB DNA-labeling system for...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Germier, Thomas, Kocanova, Silvia, Walther, Nike, Bancaud, Aurélien, Shaban, Haitham Ahmed, Sellou, Hafida, Politi, Antonio Zaccaria, Ellenberg, Jan, Gallardo, Franck, Bystricky, Kerstin
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2017
Matèries:
Nucleic Acids and Genome Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627313/
https://ncbi.nlm.nih.gov/pubmed/28978433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.08.014
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