Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement

Genome dynamics are intimately linked to the regulation of gene expression, the most fundamental mechanism in biology, yet we still do not know whether the very process of transcription drives spatial organization at specific gene loci. Here, we have optimized the ANCHOR/ParB DNA-labeling system for...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Germier, Thomas, Kocanova, Silvia, Walther, Nike, Bancaud, Aurélien, Shaban, Haitham Ahmed, Sellou, Hafida, Politi, Antonio Zaccaria, Ellenberg, Jan, Gallardo, Franck, Bystricky, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Nucleic Acids and Genome Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627313/
https://ncbi.nlm.nih.gov/pubmed/28978433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.08.014
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