Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development

The roles of long non-coding RNAs in cancer metabolism remain largely unexplored. Here we identify FILNC1 (FoxO-induced long non-coding RNA 1) as an energy stress-induced long non-coding RNA by FoxO transcription factors. FILNC1 deficiency in renal cancer cells alleviates energy stress-induced apopt...

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Publicat a:Nat Commun
Autors principals: Xiao, Zhen-Dong, Han, Leng, Lee, Hyemin, Zhuang, Li, Zhang, Yilei, Baddour, Joelle, Nagrath, Deepak, Wood, Christopher G., Gu, Jian, Wu, Xifeng, Liang, Han, Gan, Boyi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627275/
https://ncbi.nlm.nih.gov/pubmed/28978906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00902-z
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