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What makes the maternal X chromosome resistant to undergoing imprinted X inactivation?

In the mouse, while either X chromosome is chosen for inactivation in a random fashion in the embryonic tissue, the paternally derived X chromosome is preferentially inactivated in the extraembryonic tissues. It has been shown that the maternal X chromosome is imprinted so as not to undergo inactiva...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Autor principal: Sado, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627164/
https://ncbi.nlm.nih.gov/pubmed/28947661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0365
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