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Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease
X-chromosome inactivation (XCI) is an exemplar of epigenetic regulation that is set up as pluripotent cells differentiate. Once established, XCI is stably propagated, but can be reversed in vivo or by pluripotent reprogramming in vitro. Although reprogramming provides a useful model for inactive X (...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627160/ https://ncbi.nlm.nih.gov/pubmed/28947657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0358 |
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