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Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease

X-chromosome inactivation (XCI) is an exemplar of epigenetic regulation that is set up as pluripotent cells differentiate. Once established, XCI is stably propagated, but can be reversed in vivo or by pluripotent reprogramming in vitro. Although reprogramming provides a useful model for inactive X (...

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Detalles Bibliográficos
Publicado en:Philos Trans R Soc Lond B Biol Sci
Autores principales: Cantone, Irene, Fisher, Amanda G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627160/
https://ncbi.nlm.nih.gov/pubmed/28947657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0358
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