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Quantifying the influence of 5′-RNA modifications on RNA polymerase I activity

For ensemble and single-molecule analyses of transcription, the use of synthetic transcription elongation complexes has been a versatile and powerful tool. However, structural analyses demonstrate that short RNA substrates, often employed in these assays, would occupy space within the RNA polymerase...

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Publicat a:Biophys Chem
Autors principals: Appling, Francis D., Lucius, Aaron L., Schneider, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626657/
https://ncbi.nlm.nih.gov/pubmed/28893424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2017.08.010
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