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Multisubunit RNA Polymerase Cleavage Factors Modulate the Kinetics and Energetics of Nucleotide Incorporation: An RNA Polymerase I Case Study

All cellular RNA polymerases are influenced by protein factors that stimulate RNA polymerase-catalyzed cleavage of the nascent RNA. Despite divergence in amino acid sequence, these so-called “cleavage factors” appear to share a common mechanism of action. Cleavage factors associate with the polymera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Appling, Francis D., Schneider, David A., Lucius, Aaron L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400273/
https://ncbi.nlm.nih.gov/pubmed/28846843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00370
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