Quercetin inhibits epithelial–mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial–mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells

Quercetin, a flavone, is multifaceted, having anti-oxidative, anti-inflammatory, and anticancer properties. In the present study, we explored the effects of quercetin on the epithelial–mesenchymal transition (EMT) and invasion of pancreatic cancer cells and the underlying mechanisms. We noted that q...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Yu, Dinglai, Ye, Tingting, Xiang, Yukai, Shi, Zhehao, Zhang, Jie, Lou, Bin, Zhang, Fan, Chen, Bicheng, Zhou, Mengtao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626388/
https://ncbi.nlm.nih.gov/pubmed/29026320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S136840
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