Down-regulation of T-type Cav3.2 channels by hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1): Evidence of a signaling complex

Formation of complexes between ion channels is important for signal processing in the brain. Here we investigate the biochemical and biophysical interactions between HCN1 channels and Cav3.2 T-type channels. We found that HCN1 co-immunoprecipitated with Cav3.2 from lysates of either mouse brain or t...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Fan, Jing, Gandini, Maria A., Zhang, Fang-Xiong, Chen, Lina, Souza, Ivana A., Zamponi, Gerald W.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626362/
https://ncbi.nlm.nih.gov/pubmed/28467171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2017.1326233
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