Flex-nucleoside analogues – Novel therapeutics against filoviruses

Fleximers, a novel type of flexible nucleoside that have garnered attention due to their unprecedented activity against human coronaviruses, have now exhibited highly promising levels of activity against filoviruses. The Flex-nucleoside was the most potent against recombinant Ebola virus in Huh7 cel...

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Veröffentlicht in:Bioorg Med Chem Lett
Hauptverfasser: Yates, Mary K., Raje, Mithun R., Chatterjee, Payel, Spiropoulou, Christina F., Bavari, Sina, Flint, Mike, Soloveva, Veronica, Seley-Radtke, Katherine L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd. 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626011/
https://ncbi.nlm.nih.gov/pubmed/28465098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.04.069
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