Prostaglandin E(2) stimulates adaptive IL-22 production and promotes allergic contact dermatitis

BACKGROUND: Atopic dermatitis (AD) and allergic contact dermatitis (ACD) are both forms of eczema and are common inflammatory skin diseases with a central role of Th22-derived IL-22 in their pathogenesis. Although prostaglandin E(2) (PGE(2)) is known to promote inflammation, little is known about it...

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Publicado no:J Allergy Clin Immunol
Main Authors: Robb, Calum T., McSorley, Henry J., Lee, Jinju, Aoki, Tomohiro, Yu, Cunjing, Crittenden, Siobhan, Astier, Anne, Felton, Jennifer M, Parkinson, Nicholas, Ayele, Adane, Breyer, Richard M., Anderton, Stephen M., Narumiya, Shuh, Rossi, Adriano G., Howie, Sarah E., Guttman-Yassky, Emma, Weller, Richard B., Yao, Chengcan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626002/
https://ncbi.nlm.nih.gov/pubmed/28583370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.04.045
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