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RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis

Rab GTPases are switched from their GDP-bound inactive conformation to a GTP-bound active state by guanine nucleotide exchange factors (GEFs). The first putative GEFs isolated for Rabs are RABIF (Rab-interacting factor)/MSS4 (mammalian suppressor of Sec4) and its yeast homolog DSS4 (dominant suppres...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gulbranson, Daniel R., Davis, Eric M., Demmitt, Brittany A., Ouyang, Yan, Ye, Yihong, Yu, Haijia, Shen, Jingshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625932/
https://ncbi.nlm.nih.gov/pubmed/28894007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712176114
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