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Reexamining the origin of the directionality of myosin V

The nature of the conversion of chemical energy to directional motion in myosin V is examined by careful simulations that include two complementary methods: direct Langevin Dynamics (LD) simulations with a scaled-down potential that provided a detailed time-resolved mechanism, and kinetic equations...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Alhadeff, Raphael, Warshel, Arieh
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625930/
https://ncbi.nlm.nih.gov/pubmed/28894003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711214114
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