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Dysregulation of spliceosome gene expression in advanced prostate cancer by RNA-binding protein PSF

Developing therapeutic approaches are necessary for treating hormone-refractory prostate cancer. Activation of androgen receptor (AR) and its variants’ expression along with the downstream signals are mostly important for disease progression. However, the mechanism for marked increases of AR signals...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Takayama, Ken-ichi, Suzuki, Takashi, Fujimura, Tetsuya, Yamada, Yuta, Takahashi, Satoru, Homma, Yukio, Suzuki, Yutaka, Inoue, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625911/
https://ncbi.nlm.nih.gov/pubmed/28893982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706076114
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