RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer

Androgen receptor (AR) signaling is essential for the development of prostate cancer. Here, we report that runt-related transcription factor (RUNX1) could be a key molecule for the androgen-dependence of prostate cancer. We found RUNX1 is a target of AR and regulated positively by androgen. Our RUNX...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Takayama, Ken-ichi, Suzuki, Takashi, Tsutsumi, Shuichi, Fujimura, Tetsuya, Urano, Tomohiko, Takahashi, Satoru, Homma, Yukio, Aburatani, Hiroyuki, Inoue, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385850/
https://ncbi.nlm.nih.gov/pubmed/25537508
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