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Reverse Engineering Field Isolates of Myxoma Virus Demonstrates that Some Gene Disruptions or Losses of Function Do Not Explain Virulence Changes Observed in the Field

The coevolution of myxoma virus (MYXV) and wild European rabbits in Australia and Europe is a paradigm for the evolution of a pathogen in a new host species. Genomic analyses have identified the mutations that have characterized this evolutionary process, but defining causal mutations in the pathway...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Liu, June, Cattadori, Isabella M., Sim, Derek G., Eden, John-Sebastian, Holmes, Edward C., Read, Andrew F., Kerr, Peter J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625522/
https://ncbi.nlm.nih.gov/pubmed/28768866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01289-17
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