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Reverse Engineering Field Isolates of Myxoma Virus Demonstrates that Some Gene Disruptions or Losses of Function Do Not Explain Virulence Changes Observed in the Field

The coevolution of myxoma virus (MYXV) and wild European rabbits in Australia and Europe is a paradigm for the evolution of a pathogen in a new host species. Genomic analyses have identified the mutations that have characterized this evolutionary process, but defining causal mutations in the pathway...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Liu, June, Cattadori, Isabella M., Sim, Derek G., Eden, John-Sebastian, Holmes, Edward C., Read, Andrew F., Kerr, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625522/
https://ncbi.nlm.nih.gov/pubmed/28768866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01289-17
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