Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys

HIV broadly neutralizing antibodies (bnAbs) have been shown to occasionally display unusual virus neutralization profiles with nonsigmoidal slopes and plateaus at <100% neutralization against a variety of viruses. The significance of incomplete neutralization for the ability of bnAbs to mediate p...

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Publicado en:J Virol
Autores principales: Julg, Boris, Sok, Devin, Schmidt, Stephen D., Abbink, Peter, Newman, Ruchi M., Broge, Thomas, Linde, Caitlyn, Nkolola, Joseph, Le, Khoa, Su, David, Torabi, Julia, Pack, Melissa, Pegu, Amarendra, Allen, Todd M., Mascola, John R., Burton, Dennis R., Barouch, Dan H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625479/
https://ncbi.nlm.nih.gov/pubmed/28768869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01187-17
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