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Causal Genetic Inference Using Haplotypes as Instrumental Variables

In genomic studies with both genotypes and gene or protein expression profile available, causal effects of gene or protein on clinical outcomes can be inferred through using genetic variants as instrumental variables (IVs). The goal of introducing IV is to remove the effects of unobserved factors th...

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Bibliografische gegevens
Gepubliceerd in:Genet Epidemiol
Hoofdauteurs: Wang, Fan, Meyer, Nuala J., Walley, Keith R., Russell, James A., Feng, Rui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625343/
https://ncbi.nlm.nih.gov/pubmed/26625855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21940
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