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Catalytic asymmetric hydroxylative dearomatization of 2-naphthols: synthesis of lacinilene derivatives

An enantioselective hydroxylative dearomatization of 2-naphthols with oxaziridines has been accomplished using a N,N′-dioxide–scandium(iii) complex catalyst. Various substituted ortho-quinols could be obtained in high yields (up to 99%) and enantioselectivities (up to 95 : 5 er). This methodology co...

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Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Zhang, Yu, Liao, Yuting, Liu, Xiaohua, Xu, Xi, Lin, Lili, Feng, Xiaoming
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625263/
https://ncbi.nlm.nih.gov/pubmed/28989691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02809a
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