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Nitro-enabled catalytic enantioselective formal umpolung alkenylation of β-ketoesters

A formal umpolung strategy is presented for the enantioselective installation of an alkenyl group with a terminal double bond at a tertiary center. This one-pot two-step sequence relies on the unique features of the nitro group, which after inverting the polarity of the alkenylating agent toward the...

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Vydáno v:Chem Sci
Hlavní autoři: Choudhury, Abhijnan Ray, Manna, Madhu Sudan, Mukherjee, Santanu
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625255/
https://ncbi.nlm.nih.gov/pubmed/28989696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02232h
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